mTOR Controls Cell Cycle Progression through Its Cell Growth Effectors S6K1 and 4E-BP1/Eukaryotic Translation Initiation Factor 4E

The mammalian target of rapamycin (mTOR) integrates nutrient and mitogen signals to regulate cell growth (increased cell mass and cell size) and cell division. The immunosuppressive drug rapamycin inhibits cell cycle progression via inhibition of mTOR; however, the signaling pathways by which mTOR r...

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Bibliografische Detailangaben

Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Fingar, Diane C., Richardson, Celeste J., Tee, Andrew R., Cheatham, Lynn, Tsou, Christina, Blenis, John
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 2004
Schlagworte:	Cell Growth and Development
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303352/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14673156/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.1.200-216.2004
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