Selective Estrogen Receptor Modulators 4-Hydroxytamoxifen and Raloxifene Impact the Stability and Function of SRC-1 and SRC-3 Coactivator Proteins
Proteasome-mediated protein degradation has been implicated in playing a role in nuclear receptor-mediated gene expression; inhibition of the proteasome impairs the transcriptional activity of estrogen receptor α (ERα) and most other nuclear receptors. This coincides with blockage of agonist-depende...
שמור ב:
| הוצא לאור ב: | Mol Cell Biol |
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| Principais autores: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Taylor & Francis
2004
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303341/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14673139/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.1.14-24.2004 |
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