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Integrating positional information at the level of Smad1/5/8

The intensity of the BMP signal is determined by cell surface receptors that phosphorylate Smad1/5/8 at the C-terminus. In addition to this BMP-activated phosphorylation, recent studies have shown that sequential phosphorylations by MAPK and GSK3 kinases can negatively regulate the activity of the p...

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Bibliographic Details
Main Authors: Eivers, Edward, Fuentealba, Luis C., De Robertis, E.M.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033225/
https://ncbi.nlm.nih.gov/pubmed/18590818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2008.06.001
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