Integrating Patterning Signals: Wnt/GSK3 Regulates the Duration of the BMP/Smad1 Signal

BMP Receptors determine the intensity of BMP signals via Smad1 C-terminal phosphorylations. Here we show that a finely controlled cell biological pathway terminates this activity. The duration of the activated pSmad1(Cter) signal was regulated by sequential Smad1 linker region phosphorylations at co...

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Bibliographic Details
Main Authors: Fuentealba, Luis C., Eivers, Edward, Ikeda, Atsushi, Hurtado, Cecilia, Kuroda, Hiroki, Pera, Edgar M., De Robertis, E. M.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200633/
https://ncbi.nlm.nih.gov/pubmed/18045539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.09.027
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