A carregar...

Smad4/DPC4: A barrier against tumor progression driven by RTK/Ras/Erk and Wnt/GSK3 signaling

The tumor suppressor Smad4/DPC4 is an essential transcription factor in the TGF-β pathway that was previously thought to function constitutively. We recently reported that Smad4 activity and stability are directly regulated by 2 major signaling pathways, RTK/MAPK and Wnt/GSK3. Here we examine the mo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Demagny, Hadrien, De Robertis, Edward M
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905428/
https://ncbi.nlm.nih.gov/pubmed/27308623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723556.2014.989133
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!