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Asymmetric mitosis: Unequal segregation of proteins destined for degradation

Mitotic cell division ensures that two daughter somatic cells inherit identical genetic material. Previous work has shown that signaling by the Smad1 transcription factor is terminated by polyubiquitinylation and proteasomal degradation after essential phosphorylations by MAPK and glycogen synthase...

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Autori principali: Fuentealba, Luis C., Eivers, Edward, Geissert, Douglas, Taelman, Vincent, De Robertis, E. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2402384/
https://ncbi.nlm.nih.gov/pubmed/18511557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803027105
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