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SMAD signaling drives heart and muscle dysfunction in a Drosophila model of muscular dystrophy
Loss-of-function mutations in the genes encoding dystrophin and the associated membrane proteins, the sarcoglycans, produce muscular dystrophy and cardiomyopathy. The dystrophin complex provides stability to the plasma membrane of striated muscle during muscle contraction. Increased SMAD signaling d...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033181/ https://ncbi.nlm.nih.gov/pubmed/21138941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq528 |
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