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Distinct genetic regions modify specific muscle groups in muscular dystrophy
Phenotypic expression in the muscular dystrophies is variable, even with the identical mutation, providing strong evidence that genetic modifiers influence outcome. To identify genetic modifier loci, we used quantitative trait locus mapping in two differentially affected mouse strains with muscular...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3026347/ https://ncbi.nlm.nih.gov/pubmed/20959497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00172.2010 |
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