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Latent TGF-β–binding protein 4 modifies muscular dystrophy in mice

Most single-gene diseases, including muscular dystrophy, display a nonuniform phenotype. Phenotypic variability arises, in part, due to the presence of genetic modifiers that enhance or suppress the disease process. We employed an unbiased mapping approach to search for genes that modify muscular dy...

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Hlavní autoři: Heydemann, Ahlke, Ceco, Ermelinda, Lim, Jackie E., Hadhazy, Michele, Ryder, Pearl, Moran, Jennifer L., Beier, David R., Palmer, Abraham A., McNally, Elizabeth M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786802/
https://ncbi.nlm.nih.gov/pubmed/19884661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39845
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