Cathepsin-D, a Key Protease in Breast Cancer, Is Up-Regulated in Obese Mouse and Human Adipose Tissue, and Controls Adipogenesis

The aspartic protease cathepsin-D (cath-D) is overexpressed by human epithelial breast cancer cells and is closely correlated with poor prognosis in breast cancer. The adipocyte is one of the most prominent cell types in the tumor-microenvironment of breast cancer, and clinical studies have shown th...

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Autori principali: Masson, Olivier, Prébois, Christine, Derocq, Danielle, Meulle, Aline, Dray, Cédric, Daviaud, Danielle, Quilliot, Didier, Valet, Philippe, Muller, Catherine, Liaudet-Coopman, Emmanuelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032791/
https://ncbi.nlm.nih.gov/pubmed/21311773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016452
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