A DOSE ESCALATION, SAFETY, AND TOLERABILITY STUDY OF MN-029 IN PATIENTS WITH ADVANCED SOLID TUMORS

PURPOSE: To assess the maximum-tolerated dose (MTD), dose-limiting toxicity (DLT), safety, and tolerability of MN-209, a novel vascular disrupting agent, in patients with advanced solid tumors. STUDY DESIGN: MN-029 was administered weekly for 3 consecutive weeks out of 4; 2 cycles were planned. Dose...

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Main Authors: Traynor, Anne M., Gordon, Michael S., Alberti, Dona, Mendelson, David S., Munsey, Mark S., Wilding, George, Gammans, Richard E., Read, William L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032612/
https://ncbi.nlm.nih.gov/pubmed/19434370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-009-9264-2
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