Sunitinib in combination with docetaxel in patients with advanced solid tumors: a phase I dose-escalation study

PURPOSE: Sunitinib in combination with docetaxel enhances antitumor activity in xenograft models of human breast and non-small cell lung cancer. We assessed the maximum tolerated doses (MTDs), safety, pharmacokinetic profiles, and preliminary efficacy of sunitinib plus docetaxel in patients with adv...

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Main Authors: Robert, Francisco, Sandler, Alan, Schiller, Joan H., Liu, Glenn, Harper, Karen, Verkh, Lev, Huang, Xin, Ilagan, Jennifer, Tye, Lesley, Chao, Richard, Traynor, Anne M.
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2009
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904454/
https://ncbi.nlm.nih.gov/pubmed/20043166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-009-1209-0
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