Mutant Huntingtin induces activation of the Bcl-2/adenovirus E1B 19-kDa interacting protein (BNip3)

Huntington's disease (HD) is a neurodegenerative disorder characterized by progressive neuronal death in the basal ganglia and cortex. Although increasing evidence supports a pivotal role of mitochondrial dysfunction in the death of patients' neurons, the molecular bases for mitochondrial...

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Detalles Bibliográficos
Main Authors: Sassone, J, Colciago, C, Marchi, P, Ascardi, C, Alberti, L, Di Pardo, A, Zippel, R, Sipione, S, Silani, V, Ciammola, A
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2010
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032515/
https://ncbi.nlm.nih.gov/pubmed/21364626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2009.6
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