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Defining the role of the Bcl-2 family proteins in Huntington's disease
B-cell lymphoma 2 (Bcl-2) family proteins regulate survival, mitochondria morphology dynamics and metabolism in many cell types including neurons. Huntington's disease (HD) is a neurodegenerative disorder caused by an expanded CAG repeat tract in the IT15 gene that encodes for the protein hunti...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3763461/ https://ncbi.nlm.nih.gov/pubmed/23949221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.300 |
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