Defining the role of the Bcl-2 family proteins in Huntington's disease

B-cell lymphoma 2 (Bcl-2) family proteins regulate survival, mitochondria morphology dynamics and metabolism in many cell types including neurons. Huntington's disease (HD) is a neurodegenerative disorder caused by an expanded CAG repeat tract in the IT15 gene that encodes for the protein hunti...

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Detalhes bibliográficos
Main Authors: Sassone, J, Maraschi, A, Sassone, F, Silani, V, Ciammola, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763461/
https://ncbi.nlm.nih.gov/pubmed/23949221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.300
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