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Imaging Cancer Using PET – the Effect of the Bifunctional Chelator on the Biodistribution of a (64)Cu-Labeled Antibody

INTRODUCTION: Use of copper radioisotopes in antibody radiolabeling is challenged by reported loss of the radionuclide from the bifunctional chelator used to label the protein. The objective of this study was to investigate the relationship between the thermodynamic stability of the (64)Cu-complexes...

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Autores principales: Dearling, Jason L.J., Voss, Stephan D., Dunning, Patricia, Snay, Erin, Fahey, Frederic, Smith, Suzanne V., Huston, James S., Meares, Claude F., Treves, S. Ted, Packard, Alan B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032412/
https://ncbi.nlm.nih.gov/pubmed/21220127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2010.07.003
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