Imaging Cancer Using PET – the Effect of the Bifunctional Chelator on the Biodistribution of a (64)Cu-Labeled Antibody

INTRODUCTION: Use of copper radioisotopes in antibody radiolabeling is challenged by reported loss of the radionuclide from the bifunctional chelator used to label the protein. The objective of this study was to investigate the relationship between the thermodynamic stability of the (64)Cu-complexes...

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Detalhes bibliográficos
Main Authors: Dearling, Jason L.J., Voss, Stephan D., Dunning, Patricia, Snay, Erin, Fahey, Frederic, Smith, Suzanne V., Huston, James S., Meares, Claude F., Treves, S. Ted, Packard, Alan B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032412/
https://ncbi.nlm.nih.gov/pubmed/21220127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2010.07.003
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