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Primate antibody response to immunotoxin: serological and computer-aided analysis of epitopes on a truncated form of Pseudomonas exotoxin.

NLysPE38 is a 38-kDa derivative of Pseudomonas exotoxin (PE) in which domain Ia (amino acids 1 to 252) and part of domain Ib (365 to 380) are deleted and an 11-amino-acid N-terminal peptide is added. LMB-1 is an immunotoxin in which the monoclonal antibody B3 is coupled to NLysPE38 near its N termin...

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Vydáno v:Infect Immun
Hlavní autoři: Roscoe, D M, Jung, S H, Benhar, I, Pai, L, Lee, B K, Pastan, I
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1994
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303226/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7927788/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.11.5055-5065.1994
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