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Molecular mechanisms of sarcomere dysfunction in dilated and hypertrophic cardiomyopathy

The sarcomeres form the molecular motor of the cardiomyocyte and consist of a complex multi-protein of thick and thin filaments which are anchored to the cytoskeleton. The thick filament, composed of myosin and associated proteins, and the thin filament composed of actin, tropomyosin and the troponi...

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Detalhes bibliográficos
Main Authors: Frazier, Aisha H., Ramirez-Correa, Genaro A., Murphy, Anne M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032173/
https://ncbi.nlm.nih.gov/pubmed/21297871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ppedcard.2010.11.006
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