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Molecular mechanisms of sarcomere dysfunction in dilated and hypertrophic cardiomyopathy

The sarcomeres form the molecular motor of the cardiomyocyte and consist of a complex multi-protein of thick and thin filaments which are anchored to the cytoskeleton. The thick filament, composed of myosin and associated proteins, and the thin filament composed of actin, tropomyosin and the troponi...

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Bibliografiske detaljer
Main Authors: Frazier, Aisha H., Ramirez-Correa, Genaro A., Murphy, Anne M.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032173/
https://ncbi.nlm.nih.gov/pubmed/21297871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ppedcard.2010.11.006
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