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Enhancement of Antiviral Immunity by Small Molecule Antagonist of Suppressor of Cytokine Signaling
Suppressors of cytokine signaling (SOCSs) are negative regulators of both innate and adaptive immunity via inhibition of signaling by cytokines such as type I and type II IFNs. We have developed a small peptide antagonist of SOCS-1 that corresponds to the activation loop of JAK2. SOCS-1 inhibits bot...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3031960/ https://ncbi.nlm.nih.gov/pubmed/20543109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902895 |
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