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HSV-1 Induced SOCS-1 Expression in Keratinocytes: Use of a SOCS-1 Antagonist to Block a Novel Mechanism of Viral Immune Evasion
Keratinocytes are important for the acute phase of herpes simplex virus 1 (HSV-1) infection and subsequent persistence in sensory nervous tissue. In this study, we showed that keratinocytes (HEL-30) were refractory to IFNγ induction of an antiviral state to HSV-1 infection, while IFNγ did induce an...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2706942/ https://ncbi.nlm.nih.gov/pubmed/19542368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900570 |
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