Tumour suppressor microRNA-584 directly targets oncogene Rock-1 and decreases invasion ability in human clear cell renal cell carcinoma

BACKGROUND: The purpose of this study was to identify new tumour suppressor microRNAs (miRs) in clear cell renal cell carcinoma (ccRCC), carry out functional analysis of their suppressive role and identify their specific target genes. METHODS: To explore suppressor miRs in RCC, miR microarray and re...

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Detalhes bibliográficos
Main Authors: Ueno, K, Hirata, H, Shahryari, V, Chen, Y, Zaman, M S, Singh, K, Tabatabai, Z L, Hinoda, Y, Dahiya, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031891/
https://ncbi.nlm.nih.gov/pubmed/21119662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6606028
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