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Fragmentation of Fibronectin by Inherent Autolytic and Matrix Metalloproteinase Activities

Fibronectin (FN) purified by gelatin affinity chromatography is unstable and undergoes fragmentation. The cleavage has been ascribed to inherent autolytic protease activities as well as co-purified matrix metalloproteinases (MMP). Understanding the mechanism by which the proteolysis of FN occurs is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Steffensen, Bjorn, Chen, Zhihua, Pal, Sanjay, Mikhailova, Margarita, Su, Jianrong, Wang, Yao, Xu, Xiaoping
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031671/
https://ncbi.nlm.nih.gov/pubmed/20932906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2010.09.004
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