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Fragmentation of Fibronectin by Inherent Autolytic and Matrix Metalloproteinase Activities

Fibronectin (FN) purified by gelatin affinity chromatography is unstable and undergoes fragmentation. The cleavage has been ascribed to inherent autolytic protease activities as well as co-purified matrix metalloproteinases (MMP). Understanding the mechanism by which the proteolysis of FN occurs is...

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Detalhes bibliográficos
Main Authors: Steffensen, Bjorn, Chen, Zhihua, Pal, Sanjay, Mikhailova, Margarita, Su, Jianrong, Wang, Yao, Xu, Xiaoping
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031671/
https://ncbi.nlm.nih.gov/pubmed/20932906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2010.09.004
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