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Detection and Removal of Biases in the Analysis of Next-Generation Sequencing Reads

Since the emergence of next-generation sequencing (NGS) technologies, great effort has been put into the development of tools for analysis of the short reads. In parallel, knowledge is increasing regarding biases inherent in these technologies. Here we discuss four different biases we encountered wh...

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Detalles Bibliográficos
Main Authors: Schwartz, Schraga, Oren, Ram, Ast, Gil
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031631/
https://ncbi.nlm.nih.gov/pubmed/21304912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016685
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