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Detection and Removal of Biases in the Analysis of Next-Generation Sequencing Reads

Since the emergence of next-generation sequencing (NGS) technologies, great effort has been put into the development of tools for analysis of the short reads. In parallel, knowledge is increasing regarding biases inherent in these technologies. Here we discuss four different biases we encountered wh...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schwartz, Schraga, Oren, Ram, Ast, Gil
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031631/
https://ncbi.nlm.nih.gov/pubmed/21304912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016685
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