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Detection and Removal of Biases in the Analysis of Next-Generation Sequencing Reads

Since the emergence of next-generation sequencing (NGS) technologies, great effort has been put into the development of tools for analysis of the short reads. In parallel, knowledge is increasing regarding biases inherent in these technologies. Here we discuss four different biases we encountered wh...

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Detalhes bibliográficos
Main Authors: Schwartz, Schraga, Oren, Ram, Ast, Gil
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031631/
https://ncbi.nlm.nih.gov/pubmed/21304912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016685
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