Peripheral Delivery of a CNS Targeted, Metalo-Protease Reduces Aβ Toxicity in a Mouse Model of Alzheimer's Disease

Alzheimer's disease (AD), an incurable, progressive neurodegenerative disorder, is the most common form of dementia. Therapeutic options have been elusive due to the inability to deliver proteins across the blood-brain barrier (BBB). In order to improve the therapeutic potential for AD, we util...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Spencer, Brian, Marr, Robert A., Gindi, Ryan, Potkar, Rewati, Michael, Sarah, Adame, Anthony, Rockenstein, Edward, Verma, Inder M., Masliah, Eliezer
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2011
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031588/
https://ncbi.nlm.nih.gov/pubmed/21304989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016575
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