Sequential treatment of CD34(+) cells from patients with primary myelofibrosis with chromatin-modifying agents eliminate JAK2V617F-positive NOD/SCID marrow repopulating cells

Because primary myelofibrosis (PMF) originates at the level of the pluripotent hematopoietic stem cell (HSC), we examined the effects of various therapeutic agents on the in vitro and in vivo behavior of PMF CD34(+) cells. Treatment of PMF CD34(+) cells with chromatin-modifying agents (CMAs) but not...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Wang, Xiaoli, Zhang, Wei, Tripodi, Joseph, Lu, Min, Xu, Mingjiang, Najfeld, Vesna, Li, Yan, Hoffman, Ronald
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2010
Assuntos:
Myeloid Neoplasia
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031385/
https://ncbi.nlm.nih.gov/pubmed/20858855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-02-269696
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares