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Phosphatase and tensin homologue/protein kinase B pathway linked to motor neuron survival in human superoxide dismutase 1-related amyotrophic lateral sclerosis

Gene expression profiling has been used previously with spinal cord homogenates and laser capture microdissected motor neurons to determine the mechanisms involved in neurodegeneration in amyotrophic lateral sclerosis. However, while cellular and animal model work has focused on superoxide dismutase...

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Detalhes bibliográficos
Main Authors: Kirby, Janine, Ning, Ke, Ferraiuolo, Laura, Heath, Paul R., Ismail, Azza, Kuo, Su-Wei, Valori, Chiara F., Cox, Laura, Sharrack, Basil, Wharton, Stephen B., Ince, Paul G., Shaw, Pamela J., Azzouz, Mimoun
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030763/
https://ncbi.nlm.nih.gov/pubmed/21228060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awq345
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