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Antigen-specific splenic CD4(+) and CD8(+) regulatory T cells generated via the eye, suppress Experimental Autoimmune Encephalomyelitis either at the priming or at the effector phase

The injection of antigen into the ocular anterior chamber (AC) induces the generation of splenic CD4(+) and CD8(+) regulatory T (Treg) cells, specific for the antigen injected into the AC. These Treg cells inhibit the induction (CD4(+)) and also the expression (CD8(+)) of a delayed-type hypersensiti...

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Hlavní autoři: Bhowmick, Sourojit, Clark, Robert B., Brocke, Stefan, Cone, Robert E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030727/
https://ncbi.nlm.nih.gov/pubmed/21273399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxq461
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