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Recombinant human Factor VIIa (rFVIIa) cleared principally by antithrombin following IV administration in Haemophilia Patients

The objective of the present study was to evaluate the pharmacokinetics and the clearance pathways of rFVIIa after intravenous administration to haemophilia patients. Methods: Ten severe haemophilia patients were included in the study; all patients were intravenously administered a clinical relevant...

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Detalhes bibliográficos
Main Authors: Agersø, Henrik, Brophy, Donald F., Pelzer, Hermann, Martin, Erika J., Carr, Marcus, Hedner, Ulla, Ezban, Mirella
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030656/
https://ncbi.nlm.nih.gov/pubmed/21114621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2010.04152.x
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