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Bio-distribution of pharmacologically administered recombinant factor VIIa (rFVIIa)

BACKGROUND: Recent clinical studies suggest that the prophylactic use of recombinant factor VIIa (rFVIIa) markedly reduces the number of bleeding episodes in hemophilic patients with inhibitors. Given the short biological half-life of rFVIIa, it is unclear how rFVIIa could be effective in prophylact...

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Detalhes bibliográficos
Main Authors: Gopalakrishnan, R., Hedner, U., Ghosh, S., Nayak, R. C., Allen, T. C., Pendurthi, U. R., Rao, L. V. M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849270/
https://ncbi.nlm.nih.gov/pubmed/19943873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2009.03696.x
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