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Discovering Conformational Sub-States Relevant to Protein Function

BACKGROUND: Internal motions enable proteins to explore a range of conformations, even in the vicinity of native state. The role of conformational fluctuations in the designated function of a protein is widely debated. Emerging evidence suggests that sub-groups within the range of conformations (or...

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Autors principals: Ramanathan, Arvind, Savol, Andrej J., Langmead, Christopher J., Agarwal, Pratul K., Chennubhotla, Chakra S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030567/
https://ncbi.nlm.nih.gov/pubmed/21297978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015827
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