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Complement Factor H Deficiency Accelerates Development of Lupus Nephritis

Complement factor H (CfH) is a key regulator of the alternative pathway, and its presence on mouse platelets and podocytes allows the processing of immune complexes. Because of the role of immune complexes in the pathophysiology of lupus nephritis, we studied the role of CfH in the development of ne...

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Detalhes bibliográficos
Main Authors: Bao, Lihua, Haas, Mark, Quigg, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029901/
https://ncbi.nlm.nih.gov/pubmed/21148254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010060647
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