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Complement Factor H Deficiency Accelerates Development of Lupus Nephritis

Complement factor H (CfH) is a key regulator of the alternative pathway, and its presence on mouse platelets and podocytes allows the processing of immune complexes. Because of the role of immune complexes in the pathophysiology of lupus nephritis, we studied the role of CfH in the development of ne...

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Главные авторы: Bao, Lihua, Haas, Mark, Quigg, Richard J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Nephrology 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029901/
https://ncbi.nlm.nih.gov/pubmed/21148254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010060647
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