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Archaeal 3′-phosphate RNA splicing ligase characterization identifies the missing component in tRNA maturation
Intron removal from tRNA precursors involves cleavage by a tRNA splicing endonuclease to yield tRNA 3′-halves beginning with a 5′-hydroxyl, and 5′-halves ending in a 2′,3′-cyclic phosphate. A tRNA ligase then incorporates this phosphate into the internucleotide bond that joins the two halves. Althou...
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| Main Authors: | , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
National Academy of Sciences
2011
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3029724/ https://ncbi.nlm.nih.gov/pubmed/21209330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018307108 |
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