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Archaeal 3′-phosphate RNA splicing ligase characterization identifies the missing component in tRNA maturation

Intron removal from tRNA precursors involves cleavage by a tRNA splicing endonuclease to yield tRNA 3′-halves beginning with a 5′-hydroxyl, and 5′-halves ending in a 2′,3′-cyclic phosphate. A tRNA ligase then incorporates this phosphate into the internucleotide bond that joins the two halves. Althou...

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Bibliografiset tiedot
Päätekijät: Englert, Markus, Sheppard, Kelly, Aslanian, Aaron, Yates, John R., Söll, Dieter
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029724/
https://ncbi.nlm.nih.gov/pubmed/21209330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018307108
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