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A mutant toxin of Vibrio parahaemolyticus thermostable direct hemolysin which has lost hemolytic activity but retains ability to bind to erythrocytes.
A mutant toxin, R7, of thermostable direct hemolysin (TDH) with a single amino acid substitution at glycine 62 was analyzed. The hemolytic activity of R7 decreased to less than 1/1,000 of that of wild-type TDH, and its mouse lethality was undetectable. This mutant toxin, however, showed a marked inh...
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Asıl Yazarlar: | , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
1994
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC302959/ https://ncbi.nlm.nih.gov/pubmed/8039901 |
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