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A mutant toxin of Vibrio parahaemolyticus thermostable direct hemolysin which has lost hemolytic activity but retains ability to bind to erythrocytes.

A mutant toxin, R7, of thermostable direct hemolysin (TDH) with a single amino acid substitution at glycine 62 was analyzed. The hemolytic activity of R7 decreased to less than 1/1,000 of that of wild-type TDH, and its mouse lethality was undetectable. This mutant toxin, however, showed a marked inh...

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Main Authors: Tang, G Q, Iida, T, Yamamoto, K, Honda, T
格式: Artigo
語言:Inglês
出版: 1994
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC302959/
https://ncbi.nlm.nih.gov/pubmed/8039901
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