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Association of Vibrio parahaemolyticus Thermostable Direct Hemolysin with Lipid Rafts Is Essential for Cytotoxicity but Not Hemolytic Activity

Thermostable direct hemolysin (TDH), a major virulence factor of Vibrio parahaemolyticus, induces cytotoxicity in cultured cells. However, the mechanism of TDH's cytotoxic effect including its target molecules on the plasma membrane of eukaryotic cells remains unclear. In this study, we identif...

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Detalhes bibliográficos
Main Authors: Matsuda, Shigeaki, Kodama, Toshio, Okada, Natsumi, Okayama, Kanna, Honda, Takeshi, Iida, Tetsuya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812206/
https://ncbi.nlm.nih.gov/pubmed/19933828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00946-09
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