Association of Vibrio parahaemolyticus Thermostable Direct Hemolysin with Lipid Rafts Is Essential for Cytotoxicity but Not Hemolytic Activity

Thermostable direct hemolysin (TDH), a major virulence factor of Vibrio parahaemolyticus, induces cytotoxicity in cultured cells. However, the mechanism of TDH's cytotoxic effect including its target molecules on the plasma membrane of eukaryotic cells remains unclear. In this study, we identif...

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Autores principales: Matsuda, Shigeaki, Kodama, Toshio, Okada, Natsumi, Okayama, Kanna, Honda, Takeshi, Iida, Tetsuya
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Materias:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812206/
https://ncbi.nlm.nih.gov/pubmed/19933828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00946-09
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