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Conformational Conversion during Amyloid Formation at Atomic Resolution

Numerous studies of amyloid assembly have indicated that partially folded protein species are responsible for initiating aggregation. Despite their importance, the structural and dynamic features of amyloidogenic intermediates and the molecular details of how they cause aggregation remain elusive. H...

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Main Authors: Eichner, Timo, Kalverda, Arnout P., Thompson, Gary S., Homans, Steve W., Radford, Sheena E.
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029554/
https://ncbi.nlm.nih.gov/pubmed/21255727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.11.028
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