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Conformational Conversion during Amyloid Formation at Atomic Resolution

Numerous studies of amyloid assembly have indicated that partially folded protein species are responsible for initiating aggregation. Despite their importance, the structural and dynamic features of amyloidogenic intermediates and the molecular details of how they cause aggregation remain elusive. H...

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Autori principali: Eichner, Timo, Kalverda, Arnout P., Thompson, Gary S., Homans, Steve W., Radford, Sheena E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029554/
https://ncbi.nlm.nih.gov/pubmed/21255727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.11.028
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