Epigenetic investigation of variably X chromosome inactivated genes in monozygotic female twins discordant for primary biliary cirrhosis

Primary biliary cirrhosis (PBC) is an autoimmune chronic cholestatic liver disease with a strong genetic susceptibility due to the high concordance in monozygotic (MZ) twins and a striking female predominance. Women with PBC manifest an enhanced X monosomy rate in peripheral lymphocytes and we thus...

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Autors principals: Mitchell, Michelle M, Lleo, Ana, Zammataro, Luca, Mayo, Marlyn J, Invernizzi, Pietro, Bach, Nancy, Shimoda, Shinji, Gordon, Stuart C, Podda, Mauro, Gershwin, M Eric, Selmi, Carlo, LaSalle, Janine M
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029486/
https://ncbi.nlm.nih.gov/pubmed/20864813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.6.1.13405
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