The detection of the nitrite reductase and NO-generating properties of haemoglobin by mitochondrial inhibition

AIMS: Nitrite (NO(2)(−)), now regarded as an endocrine reserve of nitric oxide (NO), is bioactivated by nitrite reductase enzymes to mediate physiological responses. In blood, haemoglobin (Hb) catalyses nitrite reduction through a reaction modulated by haem redox potential and oxygen saturation, res...

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Main Authors: Shiva, Sruti, Rassaf, Tienush, Patel, Rakesh P., Gladwin, Mark T.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Original Articles: Focus on Inorganic Nitrite and Nitrate
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028973/
https://ncbi.nlm.nih.gov/pubmed/20952414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq327
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