Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control

Hypoxic vasodilation is a fundamental, highly conserved physiological response that requires oxygen and/or pH sensing coupled to vasodilation. While this process was first characterized more than 80 years ago, the precise identity and mechanism of the oxygen sensor and mediators of vasodilation rema...

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Detalhes bibliográficos
Main Authors: Huang, Zhi, Shiva, Sruti, Kim-Shapiro, Daniel B., Patel, Rakesh P., Ringwood, Lorna A., Irby, Cynthia E., Huang, Kris T., Ho, Chien, Hogg, Neil, Schechter, Alan N., Gladwin, Mark T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1177999/
https://ncbi.nlm.nih.gov/pubmed/16041407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24650
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