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HIV-1 Maturation Inhibitor Bevirimat Stabilizes the Immature Gag Lattice

Maturation of nascent virions, a key step in retroviral replication, involves cleavage of the Gag polyprotein by the viral protease into its matrix (MA), capsid (CA), and nucleocapsid (NC) components and their subsequent reorganization. Bevirimat (BVM) defines a new class of antiviral drugs termed m...

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Hlavní autoři: Keller, Paul W., Adamson, Catherine S., Heymann, J. Bernard, Freed, Eric O., Steven, Alasdair C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028903/
https://ncbi.nlm.nih.gov/pubmed/21106735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01926-10
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