Susceptibility of Human Immunodeficiency Virus Type 1 to the Maturation Inhibitor Bevirimat Is Modulated by Baseline Polymorphisms in Gag Spacer Peptide 1

In this study, we evaluated baseline susceptibility to bevirimat (BVM), the first in a new class of antiretroviral agents, maturation inhibitors. We evaluated susceptibility to BVM by complete gag genotypic and phenotypic testing of 20 patient-derived human immunodeficiency virus type 1 isolates and...

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Détails bibliographiques
Auteurs principaux: Van Baelen, Kurt, Salzwedel, Karl, Rondelez, Evelien, Van Eygen, Veerle, De Vos, Stephanie, Verheyen, Ann, Steegen, Kim, Verlinden, Yvan, Allaway, Graham P., Stuyver, Lieven J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
Sujets:
Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681549/
https://ncbi.nlm.nih.gov/pubmed/19223634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01650-08
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