Structure-Function Analyses Point to a Polynucleotide-Accommodating Groove Essential for APOBEC3A Restriction Activities

Members of the human APOBEC3 family of editing enzymes can inhibit various mobile genetic elements. APOBEC3A (A3A) can block the retrotransposon LINE-1 and the parvovirus adeno-associated virus type 2 (AAV-2) but does not inhibit retroviruses. In contrast, APOBEC3G (A3G) can block retroviruses but h...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Bulliard, Yannick, Narvaiza, Iñigo, Bertero, Alessandro, Peddi, Shyam, Röhrig, Ute F., Ortiz, Millán, Zoete, Vincent, Castro-Díaz, Nataly, Turelli, Priscilla, Telenti, Amalio, Michielin, Olivier, Weitzman, Matthew D., Trono, Didier
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2011
Teme:
Genetic Diversity and Evolution
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028873/
https://ncbi.nlm.nih.gov/pubmed/21123384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01651-10
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items