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Receptor Binding Profiles of Avian Influenza Virus Hemagglutinin Subtypes on Human Cells as a Predictor of Pandemic Potential

The host adaptation of influenza virus is partly dependent on the sialic acid (SA) isoform bound by the viral hemagglutinin (HA). Avian influenza viruses preferentially bind the α-2,3 SA and human influenza viruses the α-2,6 isoform. Each isoform is predominantly associated with different surface ep...

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Bibliografske podrobnosti
Main Authors: Shelton, Holly, Ayora-Talavera, Guadalupe, Ren, Junyuan, Loureiro, Silvia, Pickles, Raymond J., Barclay, Wendy S., Jones, Ian M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028872/
https://ncbi.nlm.nih.gov/pubmed/21106732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01822-10
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