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Nasal Immunization with a Fusion Protein Consisting of the Hemagglutinin A Antigenic Region and the Maltose-Binding Protein Elicits CD11c(+) CD8(+) Dendritic Cells for Induced Long-Term Protective Immunity

We assessed the efficacy of a fusion protein consisting of the 25-kDa antigenic region of Porphyromonas gingivalis hemagglutinin A and the Escherichia coli maltose-binding protein (25k-hagA-MBP) as a nasal vaccine for the prevention of oral infection with P. gingivalis. Nasal immunization with 25k-h...

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Detalhes bibliográficos
Main Authors: Du, Yuan, Hashizume, Tomomi, Kurita-Ochiai, Tomoko, Yuzawa, Satoshi, Abiko, Yoshimitsu, Yamamoto, Masafumi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028867/
https://ncbi.nlm.nih.gov/pubmed/21115722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01203-10
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