Adenosine Deaminase Inhibition Prevents Clostridium difficile Toxin A-Induced Enteritis in Mice

Toxin A (TxA) is able to induce most of the classical features of Clostridium difficile-associated disease in animal models. The objective of this study was to determine the effect of an inhibitor of adenosine deaminase, EHNA [erythro-9-(2-hydroxy-3-nonyl)-adenine], on TxA-induced enteritis in C57BL...

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Detalhes bibliográficos
Main Authors: de Araújo Junqueira, Ana Flávia Torquato, Dias, Adriana Abalen Martins, Vale, Mariana Lima, Spilborghs, Graziela Machado Gruner Turco, Bossa, Aline Siqueira, Lima, Bruno Bezerra, Carvalho, Alex Fiorini, Guerrant, Richard Littleton, Ribeiro, Ronaldo Albuquerque, Brito, Gerly Anne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028843/
https://ncbi.nlm.nih.gov/pubmed/21115723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01159-10
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