Raltegravir Is a Substrate for SLC22A6: a Putative Mechanism for the Interaction between Raltegravir and Tenofovir

The identification of transporters of the HIV integrase inhibitor raltegravir could be a factor in an understanding of the pharmacokinetic-pharmacodynamic relationship and reported drug interactions of raltegravir. Here we determined whether raltegravir was a substrate for ABCB1 or the influx transp...

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Bibliografische gegevens
Hoofdauteurs: Moss, Darren M., Kwan, Wai San, Liptrott, Neill J., Smith, Darren L., Siccardi, Marco, Khoo, Saye H., Back, David J., Owen, Andrew
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2011
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028780/
https://ncbi.nlm.nih.gov/pubmed/21078936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00623-10
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